Today I found following guidelines for tuning Windows Server 2012 R2 performance.

msdn.microsoft.com/en-us/library/windows/hardware/dn529133.aspx

A downloadable version of these guidelines are available here.

When you run a server system in your organization, you might have business needs that are not met by using the default settings. For example, you might need the lowest possible energy consumption, or the lowest possible latency, or the maximum possible throughput on your server. This topic provides a set of guidelines that you can use to tune the server settings in Windows Server 2012 R2 and obtain incremental performance or energy efficiency gains, especially when the nature of the workload varies little over time.